Run for their lives - Post-Acute Infection Syndromes research
Still to go
Every year, millions of people develop long-lasting health problems after an infection. These conditions, known as Post-Acute Infection Syndromes (PAIS), can drastically affect their lives. Think of long-COVID, post-treatment Lyme disease syndrome, and post-sepsis syndromes—all examples of PAIS.
People with PAIS often struggle with extreme fatigue, pain, brain fog, and reduced quality of life for months or even years. Many of them cannot work, study, or participate in daily activities, while healthcare providers often have no clear answers. Despite the enormous personal and societal impact, we still understand very little about why some people recover fully after an infection, while others develop long-term problems. There are few effective treatments, and patients are often left in uncertainty.
That is why more research is urgently needed. Research that looks beyond individual diseases, focuses on shared mechanisms, and brings together experts from different fields.
At the Amsterdam Institute for Immunology & Infectious Diseases (AI&I), part of Amsterdam UMC, we have made PAIS one of our top priorities. With over 1,100 researchers, AI&I has world-leading expertise in infections, immunity, and patient care. We already collaborate with top national and international partners, making us perfectly positioned to tackle this challenge.
JOIN THE RUN
To accelerate PAIS research, join the Lentemarathon Amstelveen 2026 and get sponsored to raise funds for PAIS research. We aim to support innovative research projects that will improve diagnostics, treatments, and quality of life for PAIS patients.
Every donation brings us closer to answers — and to giving patients the care they deserve. We invite you to join us: Run for their lives! Together, we can make a difference.
